Tim O'Donnell

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Consulting

I find it very satisfying to work closely with clients to develop new therapies and technologies. I approach consulting as a scientific collaboration, and I put a lot of energy into fully understanding the scientific and business context for each problem I take on.

I focus on two problem domains:

  • Tumor immunity and immuno-informatics
    Cancer antigen discovery and T cell epitope prediction, bioinformatic workflows for clinical application of cancer vaccines, design and analysis of sequencing, immunopeptidomics or immunoprofiling experiments

  • Protein design for vaccines and biologics
    Engineered immunogens, computationally-informed library design, de-immunization of biologics

The deliverables for my projects are typically candidate sequences/compounds, predictive models, or software. I also advise on technical strategy, hiring, experimental design, bioinformatic approaches, and software engineering practice.

I give preference to projects that have the potential to address a major unmet medical need. I have worked with multinational corporations, preclinical and clinical-stage biotech companies, and academic medical institutions.

Please reach out if you would like to discuss a possible project.